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Chemical Structure : Plerixafor octahydrochloride
CAS No.: 155148-31-5
Catalog No.: PC-45905Not For Human Use, Lab Use Only.
Plerixafor octahydrochloride (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $78 | In stock | |
| 25 mg | $158 | In stock | |
| 100 mg | $338 | In stock | |
| 1 g | Get quote |
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Plerixafor octahydrochloride (JM-3100, AMD-3100, SID-791) is a potent, selective CXCR4 inhibitor (IC50=44 nM) that inhibits the replication of various HIV-1 and HIV-2 strains in various cell lines with EC50 of 10ng/ml; can produce mesenchymal stem cells and endothelial progenitor cells in mice in combination with VEGF; also is an allosteric agonist of CXCR7.
Multiple Sclerosis
Preclinical
| M.Wt | 794.4695 | |
| Formula | C28H62Cl8N8 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: ≥ 42 mg/mL |
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| Chemical Name/SMILES |
1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride (1:8) |
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1. Zabel BA, et al. J Immunol. 2009, 183(5), 3204-3211.
2. De Clercq E, et al. Antimicrob Agents Chemother. 1994 Apr;38(4):668-74.
3. Pitchford SC, et al. Cell Stem Cell. 2009 Jan 9;4(1):62-72.
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