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Chemical Structure : RU-A1
Catalog No.: PC-61790Not For Human Use, Lab Use Only.
RU-A1 is a novel potent BMI1 inhibitor that targets cellular self-renewal in hepatocellular carcinoma (HCC).
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RU-A1 is a novel potent BMI1 inhibitor that targets cellular self-renewal in hepatocellular carcinoma (HCC).
RU-A1 downregulates BMI1 expression, impaires cell viability, reduces cell migration, and sensitizes HCC cells to 5-FU in vitro.
RU-A1 effectively reduces cancer stem-like cells (CSCs) content, and abrogates tumor growth in vivo in zebrafish.
| M.Wt | 337.401 | |
| Formula | C17H15N5OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Bartucci M, et al. Target Oncol. 2017 Aug;12(4):449-462.
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