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Chemical Structure : Revaprazan hydrochloride
Catalog No.: PC-62891Not For Human Use, Lab Use Only.
Revaprazan (SB-641257.
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Revaprazan (SB-641257;YH-1885) potent potassium-competitive acid blocker (P-CAB) that inhibits H+,K+-ATPase in a reversible and K+-competitive manner; reduces gastric acid secretion, also exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling.
Ulcer
Approved
| M.Wt | 398.91 | |
| Formula | C22H24ClFN4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Li H, et al. Drug Metab Dispos. 2001 Jan;29(1):54-9.
2. Lee JS, et al. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.
3. Inatomi N, et al. Pharmacol Ther. 2016 Dec;168:12-22.
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