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Risdiplam

Chemical Structure : Risdiplam

CAS No.: 1825352-65-5

Risdiplam (RG7916;RG-7916;RO7034067)

Catalog No.: PC-61397Not For Human Use, Lab Use Only.

Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Risdiplam (RG7916, RG-7916, RO7034067) is a highly potent, selective, orally active SMN2 splicing modifier for treatment of spinal muscular atrophy (SMA).
RG7916 is undergoing clinical trials across the spectrum of spinal muscular atrophy, where it has shown promising early results.

Physicochemical Properties

M.Wt 401.474
Formula C18H29N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one

References

1. Mammas IN, et al. Exp Ther Med. 2018 Apr;15(4):3673-3679.

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