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Risperidone mesylate

Chemical Structure : Risperidone mesylate

CAS No.: 666179-96-0

Risperidone mesylate (Apexidone;R-64766;R64766)

Catalog No.: PC-42792Not For Human Use, Lab Use Only.

An antipsychotic agent with serotonin-S2 and dopamine-D2 antagonistic properties.

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Biological Activity

An antipsychotic agent with serotonin-S2 and dopamine-D2 antagonistic properties; also has actions at several 5-HT receptor subtypes, adrenergic receptors and histamine H1 receptors.

Schizophrenia

Approved

Physicochemical Properties

M.Wt 506.5901
Formula C24H31FN4O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4H-Pyrido[1,2-a]pyrimidin-4-one, 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-, methanesulfonate (1:1)

References

1. Janssen PA, et al. J Pharmacol Exp Ther. 1988 Feb;244(2):685-93.

2. Megens AA, et al. Psychopharmacology (Berl). 1988;95(4):493-6.

3. Dugovic C, et al. Neuropharmacology. 1989 Dec;28(12):1431-3.

4. Smith C, et al. Mol Pharmacol. 2006 Oct;70(4):1264-70.

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