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S119-8

Chemical Structure : S119-8

CAS No.: 443639-96-1

S119-8 (Influenza inhibitor S119-8)

Catalog No.: PC-35387Not For Human Use, Lab Use Only.

S119-8 (Influenza inhibitor S119-8) is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM).

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Biological Activity

S119-8 (Influenza inhibitor S119-8) is a novel broad spectrum inhibitor of influenza virus replication (IC50=1.43 nM) by targeting the viral Nucleoprotein (NP), with no detectable cytotoxicity (CC50>50 uM); also shows activity against multiple influenza B viruses and an oseltamivir-resistant influenza A virus, does not inhibit a non-influenza virus, VSV; exhibits synergistic combined with in vitro viral inhibition assays.

Physicochemical Properties

M.Wt 344.458
Formula C23H24N2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzamide, 4-(1,1-dimethylethyl)-N-[4-(phenylamino)phenyl]-

References

1. White KM, et al. ACS Infect Dis. 2018 Feb 9;4(2):146-157.

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