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Chemical Structure : SLV peptide
Catalog No.: PC-61257Not For Human Use, Lab Use Only.
A tripeptide representing the Fas-C terminus that specifically blocks the interaction of Fap1 with Fas.
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SLV peptide is a tripeptide representing the Fas-C terminus that specifically blocks the interaction of Fap1 with Fas.
SLV peptide increases apoptosis sensitivity and decreases β-catenin in vitro, also decrease interaction of Fap1 with Apc, does not alter expression of Fap1 or Apc proteins.
SLV peptide induces Fas-mediated apoptosis in a colon cancer cell line that expresses both Fas and FAP-1.
| M.Wt | 317.386 | |
| Formula | C14H27N3O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Huang W, et al. Leukemia. 2016 Jul;30(7):1502-9.
2. Huang W, et al. J Biol Chem. 2013 May 3;288(18):12766-76.
3. Yanagisawa J, et al. J Biol Chem. 1997 Mar 28;272(13):8539-45.
4. Huang W, et al. Leuk Lymphoma. 2013 Mar;54(3):619-30.
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