Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : SSR125543
CAS No.: 752253-39-7
Catalog No.: PC-36089Not For Human Use, Lab Use Only.
SSR125543 (Crinecerfont, SSR-125543) is a potent, nonpeptide, orally active corticotropin-releasing factor (CRF) receptor CRF1 antagonist, shows anxiolytic- and antidepressant-like activities in vivo. .
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
SSR125543 (Crinecerfont, SSR-125543) is a potent, nonpeptide, orally active corticotropin-releasing factor (CRF) receptor CRF1 antagonist, shows anxiolytic- and antidepressant-like activities in vivo.
| M.Wt | 483.042 | |
| Formula | C27H28ClFN2OS | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(prop-2-yn-1-yl)-1,3-thiazol-2-amine |
|
1. Louis C, et al. Neuropsychopharmacology. 2006 Oct;31(10):2180-7.
2. Overstreet DH, et al. Eur J Pharmacol. 2004 Aug 16;497(1):49-53.
3. Claustre Y, et al. Neuroscience. 2006 Sep 1;141(3):1481-8.
4. Urani A, et al. Pharmacol Biochem Behav. 2011 May;98(3):425-31.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
