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Chemical Structure : T-00127-HEV1
Catalog No.: PC-63343Not For Human Use, Lab Use Only.
T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM, inhibits poliovirus pseudovirus and EV71 in RD cells with IC50 of 0.77 and 0.73 uM.
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T-00127-HEV1 is a broad-spectrum antienterovirus compound that selectively inhibits PI4KB activity with IC50 of 60 nM, inhibits poliovirus pseudovirus and EV71 in RD cells with IC50 of 0.77 and 0.73 uM; shows a moderate inhibitory effect on PIK3CD activity, and high selectivity over other PI kinases; demonstrates antipoliovirus activity ,does not inhibit hepatitis C virus (HCV) replication.
| M.Wt | 411.506 | |
| Formula | C22H29N5O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72.
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