Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : TAOK inhibitor 63
Catalog No.: PC-62818Not For Human Use, Lab Use Only.
TAOK inhibitor 63 is a novel potent, selective, ATP-competitive TAO Kinase (TAOK) inhibitor with IC50 of 19 and 39 nM against TAOK1 (MAP3K16) and TAOK2 (MAP3K17), respectively.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
TAOK inhibitor 63 is a novel potent, selective, ATP-competitive TAO Kinase (TAOK) inhibitor with IC50 of 19 and 39 nM against TAOK1 (MAP3K16) and TAOK2 (MAP3K17), respectively.
TAOK inhibitor 63 increases the mitotic population, the percentages of mitotic cells displaying amplified centrosomes and multipolar spindle.
TAOK inhibitor 63 induces cell death, and inhibits cell growth in centrosome-amplified SKBR3 or BT549 breast cancer cell models.
| M.Wt | 488.562 | |
| Formula | C26H24N4O4S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Koo CY, et al. Mol Cancer Ther. 2017 Nov;16(11):2410-2421.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
