Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : TCDD
Catalog No.: PC-61319Not For Human Use, Lab Use Only.
A potent AHR (aryl hydrocarbon receptor) agonist that induces degradation of AhR by the ubiquitin-proteasome pathway.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A potent AHR (aryl hydrocarbon receptor) agonist that induces degradation of AhR by the ubiquitin-proteasome pathway; suppresses the transcription of PEPCK and decreases Sirtuin 1 activation of PGC1α; also blocks cNK development and supports group 3 innate lymphoid cell (ILC3) differentiation.
| M.Wt | 321.96 | |
| Formula | C12H4Cl4O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Ma Q, et al. J Biol Chem. 2000 Mar 24;275(12):8432-8.
2. Diani-Moore S, et al. J Biol Chem. 2013 Jul 26;288(30):21514-25.
3. Angelos MG, et al. Blood. 2017 Jun 29;129(26):3428-3439.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
