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THS-044

Chemical Structure : THS-044

CAS No.: 62054-67-5

THS-044 (THS044;THS 044)

Catalog No.: PC-45660Not For Human Use, Lab Use Only.

THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

THS-044 is a low micromolar HIF2α PAS-B binding compound (Kd=2 uM); modulates the affinity of the HIF2α:ARNT PAS-B heterodimer in vitro.

Physicochemical Properties

M.Wt 291.2265
Formula C11H12F3N3O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Morpholinamine, N-[2-nitro-4-(trifluoromethyl)phenyl]-

References

1. Scheuermann TH, et al. Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):450-5.

2. Motto I, et al. J Chem Inf Model. 2011 Nov 28;51(11):2868-81.

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