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Chemical Structure : TTP-8307
Catalog No.: PC-62922Not For Human Use, Lab Use Only.
TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM.
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TTP-8307 is a potent inhibitor of the replication of several Rhinoviruses and Enteroviruses, targets the nonstructural protein 3A, inhibits the replication of coxsackievirus B3 (CVB3 Nancy) with EC50 of 1.2 uM; 3A mutations V45A, I54F, and H57Y confer resistance to TTP-8307.
| M.Wt | 436.49 | |
| Formula | C27H21FN4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. De Palma AM, et al. Antimicrob Agents Chemother. 2009 May;53(5):1850-7.
2. Arita M, et al. J Virol. 2011 Mar;85(5):2364-72.
3. Norder H, et al. Antiviral Res. 2011 Mar;89(3):204-18.
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