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Chemical Structure : VH-032
CAS No.: 1448188-62-2
Catalog No.: PC-60116Not For Human Use, Lab Use Only.
VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $268 | In stock | |
| 50 mg | $458 | In stock | |
| 100 mg | $788 | In stock | |
| 200 mg | Get quote | ||
| 1 g | Get quote |
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VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM.
| M.Wt | 472.604 | |
| Formula | C24H32N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
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1. Zengerle M, et al. ACS Chem Biol. 2015 Aug 21;10(8):1770-7.
2. Galdeano C, et al. J Med Chem. 2014 Oct 23;57(20):8657-63.
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