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Chemical Structure : VT-1161
CAS No.: 1340593-59-0
Catalog No.: PC-61753Not For Human Use, Lab Use Only.
VT-1161 (Oteseconazole) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $578 | In stock | |
| 100 mg | Get quote |
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VT-1161 (Oteseconazole) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM.
VT-1161 (Oteseconazole) demonstrates >2,000-fold selectivit over human CYP51, weakly inhibits human CYP2C9, CYP2C19, and CYP3A4.
VT-1161 (Oteseconazole) exhibits excellent potency against key yeast and dermatophyte strains.
| M.Wt | 527.403 | |
| Formula | C23H16F7N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol |
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1. Hoekstra WJ, et al. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3455-8.
2. Warrilow AG, et al. Antimicrob Agents Chemother. 2014 Dec;58(12):7121-7.
3. Garvey EP, et al. Antimicrob Agents Chemother. 2015 Sep;59(9):5567-73.
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