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Chemical Structure : WAY-100635 maleate
CAS No.: 634908-75-1
Catalog No.: PC-43382Not For Human Use, Lab Use Only.
WAY-100635 is a potent and selective 5-HT1A receptor antagonist.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $155 | In stock | |
| 50 mg | $275 | In stock | |
| 100 mg | $485 | In stock | |
| 500 mg | Get quote |
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WAY-100635 is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor; completely prevents not only the hyperpolarization, with an IC50 of 1.3 nM, but also the decrease in membrane input resistance produced by 5-HT and 5-carboxamidotryptamine with IC50 of 22.5 μM and 50 nM, respectively.
Anxiety
Phase 1 Discontinued
| M.Wt | 538.6352 | |
| Formula | C29H38N4O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
Cyclohexanecarboxamide, N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-, (2Z)-2-butenedioate (9CI) |
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1. Corradetti R, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):679-88.
2. Fornal CA, et al. J Pharmacol Exp Ther. 1996 Aug;278(2):752-62.
3. García G, et al. Eur J Med Chem. 2014 Oct 6;85:795-806.
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