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Chemical Structure : mPGES1-IN-16
Catalog No.: PC-62820Not For Human Use, Lab Use Only.
mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM.
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mPGES1-IN-16 is a potent and selective mPGES-1 inhibitor with IC50 of 1 nM.
mPGES1-IN-16 displays no activity against a panel of 35 receptors, ion channels, and hERG.
mPGES1-IN-16 shows IC50/IC80 of 6 nM/24 nM for inhibition of PGE2 formation in vitro in LPS-stimulated human whole blood (HWB); orally bioavailable in vivo.
| M.Wt | 485.628 | |
| Formula | C30H35N3O3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Partridge KM, et al. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1478-1483.
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