| Cat. No. |
Product Name |
Information |
| PC-62097 |
Mosapride citrate
5HT4 agonist
|
Mosapride citrate (AS-4370 citrate) is a gastroprokinetic agent that acts as a selective 5HT4 agonist. |
| PC-62096 |
Naronapride
5-HT4 agonist
|
Naronapride (ATI-7505) is a potent, selective and orally active 5-HT4 receptor agonist with Ki of 1.4 nM. |
| PC-62093 |
YH12852
5-HT4 agonist
|
YH12852 is a potent, highly selective 5-HT4 receptor agonist with pKi of 10.3, exhibits more potent agonistic activity (pEC50=11.4) than both tegaserod and prucalopride. |
| PC-61831 |
PF-04995274
|
PF-04995274 (TBPT) is a novel potent, sellective, partial agonist of 5-HT4 receptor under investigation for neurological disorders.. |
| PC-61625 |
Befiradol
|
Befiradol (F13640, NLX 112) is a highly potent, selective 5-HT1A receptor agonist with Ki of 2.7 nM. |
| PC-61522 |
SUVN-502 mesylate hydrate
|
SUVN-502 (SUVN502) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM. |
| PC-61521 |
SUVN-502 mesylate
5-HT6 antagonist
|
SUVN-502 (Masupirdine, SUVN502) mesylate is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM. |
| PC-61511 |
AVN-211
5-HT6 antagonist
|
AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM. |
| PC-61500 |
SUVN-502
5-HT6 antagonist
|
SUVN-502 (SUVN502, Masupirdine) is a potent, selective, brain penetrant and orally active 5-HT6 receptor antagonist with Ki of 2.04 nM. |
| PC-60814 |
MDL100907
5-HT2A inhibitor
|
MDL100907 (Volinanserin) is a potent, selective 5-HT2A receptor antagonist with Ki of 0.36 nM, > 80-fold selectivity for 5-HT2A over other serotonergic receptors. |
| PC-60521 |
Minesapride
|
Minesapride (DSP-6952) is a novel potent, selective, orally active 5-HT4 receptor partial agonist with Ki of 50-100 nM for human 5-HT4a/4b/4c. |
| PC-70076 |
Lumateperone
|
Lumateperone (ITI-007) is a potent 5-HT2A antagonist (Ki=0.54 nM), postsynaptic D2 antagonist(Ki=32 nM), and SERT blocker (Ki= 61 nM). |
