| Cat. No. |
Product Name |
Information |
| PC-35636 |
IITZ-01
Autophagy inhibitor
|
IITZ-01 (Autophagy inhibitor IITZ-01) is a potent lysosomotropic autophagy inhibitor, exhibits >10-fold potent autophagy inhibition along with 12- to 20-fold better cytotoxic action than Chloroquine. |
| PC-35620 |
PHY34
Autophagy inhibitor
|
PHY34 is a potent autophagy inhibitor with cytotoxic effects by inhibiting autophagy at a late stage (MDA-MB-435 IC50=23 nM, MDA-MB-231 IC50=5.2 nM). |
| PC-35046 |
Aumitin
Autophagy inhibitor
|
Aumitin is a novel potent autophagy inhibitor with IC50 of 124 and 244 nM against starvation- and rapamycin- induced autophagy respectively, targets mitochondrial complex I. |
| PC-63057 |
Elaiophylin
Autophagy inhibitor
|
Elaiophylin (Gopalamicin;Salbomycin;Azalomycin B) is a macrodiolide antibiotic and autophagy inhibitor that promotes autophagosome accumulation. |
| PC-61671 |
ZPCK
Autophagy inhibitor
|
ZPCK (NSC 251810, SL 01) is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells. |
| PC-61297 |
XRK3F2
p62 inhibitor
|
XRK3F2 is a specific ZZ-domain of ubiquitin-binding protein p62 (Sequestosome 1) inhibitor that inhibits MM cell growth and BMSC growth enhancement of human MM cells. |
| PC-70317 |
BRD5631
Autophagy inducer
|
BRD5631 is a small-molecule enhancer of autophagy through an mTOR-independent pathway. |
| PC-60602 |
Lucanthone
APE1 inhibitor
|
Lucanthone is an ionizing radiation enhancer and apurinic/apyrimidinic endonuclease 1 (APE1) inhibitor with IC50 of 5 uM for inhibition of APE1 incision of depurinated plasmid DNA, also may act as an inhibitor of protein palmitoyl thioesterase 1 (PPT1). |
| PC-60601 |
Lys05
Autophagy inhibitor, Kir4.1 inhibitor
|
Lys05 (Lys01 trihydrochloride, PS-1001) is the water-soluble salt of Lys01, is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ), also is a Kir4.1 inhibitor. |
| PC-60600 |
Lys01
Autophagy inhibitor
|
Lys01 is a 10-fold more potent lysosomal autophagy inhibitor than hydroxychloroquine (HCQ). |
| PC-60599 |
ROC-325
Autophagy inhibitor
|
ROC-325 (ROC 325, ROC325) is a novel, orally available inhibitor of lysosomal-mediated autophagy. |
| PC-60217 |
AUTEN-67
MTMR14 inhibitor, autophagy inducer
|
AUTEN-67 is a small molecule autophagy enhancer that specificly inhibits myotubularin-related phosphatase MTMR14. |
