| Cat. No. |
Product Name |
Information |
| PC-70067 |
AUTEN-99
MTMR14 inhibitor, autophagy inducer
|
AUTEN-99 is a small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-70066 |
AUTEN-99 hydrobromide
MTMR14 inhibitor, autophagy inducer
|
A small molecule autophagy enhancer that inhibit the myotubularin-related phosphatase MTMR14/Jumpy. |
| PC-45633 |
Hemin
Autophagy inducer
|
Hemin, a physiological erythroid maturation stimulator, is able to induce the expression of critical autophagic genes (Map1a1b (LC3), Beclin-1 gen, Atg5) in an erythroleukemia cell type. |
| PC-42080 |
SMER-28
VCP/p97 activator
|
SMER28 is a small-molecule enhancer/inducer of Autophagy, SMER28 is a small molecule activator of VCP/p97. |
| PC-42248 |
STF-62247
Autophagy inducer
|
STF-62247 is a small molecule Autophagy inducer that induces autophagy and selectively induces lethality in VHL-deficient RCC cells. |
| PC-45515 |
SMER-18
Autophagy inducer
|
SMER-18 is a small molecule autophagy enhancer that induces autophagy independently of rapamycin in mammalian cells and enhances the clearance of autophagy substrates such as mutant huntingtin and A53T alpha-synuclein. |
| PC-21907 |
Hycanthone
APE1 inhibitor
|
Hycanthone is a thioxanthenone DNA intercalator, inhibits RNA synthesis as well as the DNA topoisomerases I and II, inhibits apurinic endonuclease 1 (APE1) incision of depurinated plasmid DNA with IC50 of 80 nM. |
| PC-21540 |
RH1115
Autophagy activator
|
RH1115 is a small molecule activator and inducer of autophagy targeting Lamin A/C and LAMP1, induces changes to LAMP1 vesicle properties and alters lysosome positioning. |
| PC-20502 |
JS-017
A2E degrader
|
JS-017 (JS017) is a small molecule degrader of N-retinylidene-N-retinylethanolamine (A2E), one of the components of lipofuscin, degrades A2E-BDP from ARPE-19 cells with IC50 of 3.239 uM. |
| PC-38562 |
Autophagy inducer D61
Autophagy inducer
|
Autophagy inducer D61 is a small molecule autophagy inducer with antibacterial activity, induces LC3II and promotes aggregation of LC3II near Salmonella. |
| PC-60596 |
Hydroxychloroquine sulfate
|
A synthetic antimalarial drug that inhibits autophagy, also inhibits TLR7 and TLR9 signaling.. |
| PC-45984 |
Cysteamine
|
An agent for the treatment of nephropathic cystinosis and an antioxidant. |
