| Cat. No. |
Product Name |
Information |
| PC-20689 |
BAU-243
Bcl-2 inhibitor
|
BAU-243 (BAU243) is a novel BH3 mimetic Bcl-2 inhibitor with a high affinity, effectively reduces overall GBM cell proliferation including a subpopulation of cancer-initiating cells. |
| PC-20626 |
CCT373567
BCL6 inhibitor
|
CCT373567 is a potent, selective and cell-active BCL6 inhibitor with IC50 of 2.9 nM in TR-FRET assays, and 25.9 nM in NanoBRET cellular inhibition assays. |
| PC-20511 |
ABBV-167
BCL-2 inhibitor
|
ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax (Cat. PC-49764), shows significantly increased water solubility to venetoclax, demonstrates a lower food effect with respect to venetoclax. |
| PC-20503 |
CCT374705
BCL6 inhibitor
|
CCT374705 is a potent, selective, in-vivo active BCL6 inhibitor with TR-FRET IC50 of 6 nM. |
| PC-20245 |
CGDF-190-20
BFL-1 inhibitor
|
CGDF-190-20 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 365 nM in FP assays. |
| PC-20244 |
CGDF-183-20
BFL-1 inhibitor
|
CGDF-183-20 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 264 nM in FP assays. |
| PC-20243 |
BDM53787
BFL-1 inhibitor
|
BDM53787 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 0.8 uM (inhibition FITC–Bim BH3 binding to Bfl-1). |
| PC-20242 |
BDM49234
BFL-1 inhibitor
|
BDM49234 is a selective small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 6.3 uM (inhibition FITC–Bim BH3 binding to Bfl-1). |
| PC-20241 |
BDM44898
BFL-1 inhibitor
|
BDM44898 is a small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 1.6 uM. |
| PC-20240 |
BDM44931
BFL-1 inhibitor
|
BDM44931 is a small molecule inhibitor of anti-apoptotic protein BCL2A1/Bfl-1 with IC50 of 1.3 uM. |
| PC-49799 |
BM-1197
Bcl-2/Bcl-xL inhibitor
|
BM-1197 (BM1197) is a potent and efficacious dual inhibitor of Bcl-2 and Bcl-xL with Ki of < 1 nM, >1,000-fold selectivity over Mcl-1. |
| PC-49798 |
Pelcitoclax
Bcl-2/Bcl-xL inhibitor
|
Pelcitoclax (APG-1252, BM-1252) is a potent dual specific Bcl-2/Bcl-xL inhibitor with Ki of < 1 nM, shows potent antitumor effects with minimal platelet toxicity. |
