Cat. No. |
Product Name |
Information |
PC-61016 |
BCL6 inhibitor 8c
|
A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays. |
PC-60923 |
BTC-8
|
A derivative of BAM-7 that acts as a nove potent, direct activator of Bax with EC50 of 700 nM. |
PC-60922 |
Bax activator compound 106
|
A specific, small molecule Bax agonist that promotes Bax-dependent but not Bak-dependent apoptosis. |
PC-60153 |
Mcl1-IN-26
|
A novel potent, selective Mcl-1 inhibitor with IC50 of <3 nM in FRET assays. |
PC-42125 |
BH3I-1
|
A small-molecule Bcl-2 antagonist that inhibits the ineraction of Bak BH3 and Bcl-xL with Ki of 2.4 uM in FP binding assay. |
PC-45041 |
MIM1
|
A potent, selective small molecule Mcl-1 inhibitor that selectively targets the BH3-binding groove of Mcl-1. |
PC-42756 |
Obatoclax
|
A potent inhibitor of Bcl-2 family with IC50s of 1-7 uM for Bcl-2, Bcl-XL, Bcl-w, Bcl-B, Mcl-1 and Bfl-1. |
PC-45490 |
UMI-77
|
A potent and selective Mcl-1 inhibitor with Ki of 0.49 uM. |
PC-47486 |
Bax inhibitor peptide V5
|
A cell-permeable synthetic peptide inhibitor of Bax conformational change and mitochondrial translocation. |