| Cat. No. |
Product Name |
Information |
| PC-43237 |
KH-CB19
CLK1/4 inhibitor
|
KH-CB19 is a potent and highly specific inhibitor of CDC2-like kinase isoforms 1 and 4 (CLK1/CLK4) with IC50 of 20 nM (CLK1), displays almost 100-fold selectivity against the CLK3 isoform. |
| PC-61029 |
ML167
CLK4 inhibitor
|
ML167 is a potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B. |
| PC-61028 |
CGP-74514A
CDK/CLK inhibitor
|
CGP-74514A is a cell permeable, potent, and selective inhibitor of CDK1/cyclin B with IC50 of 25 nM, and CLK1, CLK2, CLK4 inhibitor. |
| PC-61027 |
SRI-29329
CLK inhibitor
|
SRI-29329 (SRI29329) is a potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and 4, respectively. |
| PC-61026 |
CLK inhibitor 2
CLK1/2 inhibitor
|
CLK inhibitor 2 is a potent, selective inhibitor of cdc2-like kinase CLK1 and CLK2 with IC50 of 1.1 and 2.4 nM, respectively. |
| PC-61025 |
Leucettine L41
CLK/DYRK inhibitor
|
Leucettine L41 is a novel potent cdc2-like kinase (CLKs) and DYRKs inhibitor with IC50 of 40, 35 and 15 nM for DYRK1A, DYRK2 and CLK1, respectively. |
| PC-61023 |
TG693
CLK1 inhibitor
|
TG693 is an orally available, selective, ATP-competitive CLK1 inhibitor with IC50 of 112.6 nM. |
| PC-61022 |
CC-671
Mps1/CLK2 inhibitor
|
CC-671 (CC671) is a potent, selective, dual TTK (Mps1)/CLK2 inhibitor with IC50 of 5/3 nM, respectively. |
| PC-61021 |
CLK inhibitor T3
CLK inhibitor
|
CLK inhibitor T3 (T3) is a highly potent, selective, and cell-based stable CDC-like kinase (CLK) inhibitor with 0.67, 15 and 110 nM for CLK1,2 and 3, respectively. |
| PC-60504 |
SM04690
CLK inhibitor
|
Adavivint (Lorecivivint, SM04690) is a novel small molecule Wnt pathway inhibitor with EC50 of 3 nM in vitro, potently inhibits CLK2 and DYRK1A with IC50 of 5.8 and 26.9 nM, respectively. |
| PC-22056 |
CLK2 inhibitor LQ23
CLK2 inhibitor
|
CLK2 inhibitor LQ23 is a potent, selective cdc2-like kinase 2 (CLK2) inhibitor with IC50 of 1.4 nM, >70-fold selecitve over CLK3.
|
| PC-21435 |
SM04755
CLK inhibitor
|
Teplinovivint (SM04755) is a small molecule canonical Wnt signaling inhibitor, potently inhibited CLK2, CLK3, and DYRK1A with IC50 of 5.0 nM, 48.6 nM and 3.5 nM, respectively. |
