Cat. No. |
Product Name |
Information |
PC-20372 |
IPG7236
CCR8 inhibitor
|
IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM. |
PC-20291 |
NUCC-390 dihydrochloride
CXCR4 agonist
|
NUCC-390 dihydrochloride (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
PC-20290 |
NUCC-390
CXCR4 agonist
|
NUCC-390 (NUCC390) is a small molecule agonist of CXCR4, recapitulates the activity of CXCL12α. |
PC-49866 |
RIST4721
CXCR2 inhibitor
|
RIST 4721 (Vimnerixin, AZD 4721) is a potent, specific and orally active antagonist of CXCR2, potently inhibits neutrophil chemotaxis with IC50 of 17 nM. |
PC-49368 |
LN6023
CXCR7 inhibitor
|
LN6023 (LN-6023) a potent, selective and first-in-class inhibitor of the atypical chemokine receptor 3 (ACKR3, CXCR7) with β-arrestin EC50 of 3.5 uM. |
PC-49265 |
ACT-660602
CXCR3 antagonist
|
ACT-660602 (ACT660602) is a potent, selective and orally bioavailable CXCR3 antagonist with IC50 of 204 nM in human blood. |
PC-49264 |
ACT-672125
CXCR3 antagonist
|
ACT-672125 (ACT672125) is a potent, selective CXCR3 antagonist with IC50 of 239 nM in human blood. |
PC-38757 |
CCR9 inhibitor 12
CCR9 inhibitor
|
CCR9 inhibitor 12 is a potent inhibitor of chemokine receptor 9 (CCR9) with IC50 of 20 nM in calcium (Ca2+) FLIPR assay, shows IC50 of 277 nM in chemotaxis assays. |
PC-38725 |
WZ811
CXCR4 inhibitor
|
WZ811 is a nonpeptidic, small molecule antagonist of CXCR4 with EC50 of 0.3 nM affinity binding assays, suppresses cancer cells aggressive in a variety of cancers. |
PC-38724 |
MSX-122
CXCR4 modulator
|
MSX-122 is a small molecule and partial CXCR4 antagonist, directly binds to the CXCL12 site on CXCR4 and inhibits CXCR4/CXCL12 actions with IC50 of 10 nM. |
PC-38704 |
DF2755A
CXCR1/2 inhibitor
|
DF2755A is a selective, allosteric, orally acting inhibitor of CXCR1/2 (Kd=2.24/0.94 nM), inhibits human PMN (hPMN) migration induced by CXCL8 and CXCL1 with IC50 of 4.2 and 2.1 nM, respectively. |
PC-38669 |
CXCR7 agonist 1
CXCR7 agonist
|
CXCR agonist 1 is a potent, selective, small molecule agonist of CXCR7 (ACKR3), induces β-arrestin recruitment to CXCR7 and Akt activation, inhibits CXCL12-induced tube formation in HUVECs with EC50 of 0.96 nM. |