Cat. No. |
Product Name |
Information |
PC-20364 |
Ani9
ANO1 (TMEM16A) inhibitor
|
Ani9 is a potent, selective anoctamin1 (ANO1, TMEM16A) channel inhibitor with IC50 of 107 nM, with negligible effect on ANO2 (IC50>10 uM). |
PC-20363 |
CaCCinh-A01
CaCC inhibitor
|
CaCCinh-A01 is a small molecule Ca(2+)-activated Cl(-) channel (CaCC) inhibitor, inhibits both I(sc) and transepithelial conductance in a concentration-dependent manner (IC50=6.3 uM). |
PC-47048 |
TMinh-23
TMEM16A inhibitor
|
TMinh-23 is (Compound 10bm) is a potent, selective inhibitor of transmembrane protein 16A (TMEM16A or ANO1, DOG1, ORAOV2, TAOS-2) with IC50 of 30 nM in short-circuit current assays, weakly inhibits TMEM16B (IC50=400 nM, 13 -fold selectivity). |
PC-38691 |
VI-116
VRAC inhibitor
|
VI-116 is a potent and selective volume-regulated anion channel (VRAC) inhibitor, fully inhibits VRAC-mediated I- quenching with an IC50 of 1.27 uM in LN215 cells. |
PC-38479 |
MONNA
TMEM16A inhibitor
|
MONNA a potent, selective inhibitor of the TMEM16A calcium-activated chloride channel (Anoctamin-1, ANO1) with IC50 of 80 nM (xANO1). |
PC-72552 |
CLC-2-IN-AK42
CLC-2 inhibitor
|
CLC-2-IN-AK42 (CLC-2 inhibitor AK42, AK42) is a potent, specific small-molecule inhibitor of voltage-gated chloride channel CLC-2 with IC50 of 17 nM (human CLC-2). |
PC-62452 |
OADS
|
OADS is a specific, reversible, small-molecule inhibitor directs against CLC (Chloride Channel) antiporter with Ki of 29 uM, has no specific effect on a CLC channel (ClC-1). . |
PC-47506 |
Chlorotoxin
|
Chlorotoxin is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus). |