| Cat. No. |
Product Name |
Information |
| PC-72466 |
SY-5102
CDK7 inhibitor
|
SY-5102 (SY5102) is a highly potent, selective, noncovalent, orally available CDK7 inhibitor with SPR Kd of 0.03 nM (binding to CDK7/Cyclin H). |
| PC-72216 |
MFH290
CDK12/13 inhibitor
|
MFH290 (MFH-290) is a potent, highly selective, covalent inhibitor of CDK12/13 with IC50 of 25/49 nM. |
| PC-38063 |
bio-THZ1
|
bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7.. |
| PC-35809 |
CDK9 inhibitor HH1
|
CDK9 inhibitor HH1 is a novel potent, highly selective CDK9 inhibitor.. |
| PC-35525 |
CDK12 inhibitor 2
|
CDK12 inhibitor 2 is a potent, selective, non-covalent CDK12 inhibitor with IC50 of 52 nM, displays >192-fold selectivity over CDK2/7/8/9. |
| PC-35248 |
Cdc7 inhibitor
|
Cdc7 inhibitor is a potent inhibitor of Cdc7 kinase with pIC50 of 10.01 against CDC7/DBF4 in TR-FRET assays.. |
| PC-43411 |
CDK9-IN-1
|
CDK9-IN-1 is a potent, selective CDK9 inhibitor with IC50 of 39 nM (CDK9/CycT1), >10-fold selectivity over CDK4 and >100-fold over CDK1/2/3/5/6/7, inhibits HIV-1 replication in cellular assays.. |
| PC-43342 |
CDK9-IN-2
|
CDK9-IN-2 is a potent and selective CDK9 inhibitor with IC50 of <8 nM, example 4 in patent WO2011026917A1.. |
| PC-43145 |
CCT251545
|
CCT251545 is a potent, orally bioavailable inhibitor of Wnt signaling with IC50 of 5 nM, also is a potent and selective chemical probe for CDK8 and CDK19 with >100-fold selectivity over 291 other kinases. |
| PC-63235 |
CDK inhibitor E9
|
CDK inhibitor E9 is a novel CDK inhibitor that can overcomes ABC-mediated resistance of THZ1, functions
as a potent, non-covalent inhibitor of CDK9 and a covalent inhibitor of CDK12. |
| PC-63209 |
Alsteropaullone
|
Alsteropaullone (9-Nitropaullone, NSC 705701) is a derivative of kenpaullone, ATP-competitive inhibitor of CDKs and GSK3β, inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E and Cdk5/p25 with IC50 of 35, 15, 200 and 40 nM. |
| PC-42965 |
Kenpaullone
|
Kenpaullone (9-Bromopaullone,NSC-664704) is a potent inhibitor of CDK1/cyclin B with IC50 of 0.4 uM, also inhibited CDK2/cyclin A (IC50=0.68 uM), CDK2/cyclin E (IC50-7.5 uM) and CDK5/p25 (IC50=0.85 uM). |
