| Cat. No. |
Product Name |
Information |
| PC-42956 |
LY2857785
|
LY2857785 is a potenrt, reversible and ATP-competitive CDK9 inhibitor with IC50 of 11 nM, also inhibits CDK8 (IC50=16 nM) and weakly inhibits CSK7 (IC50=246 nM). |
| PC-62848 |
CDK9-IN-4d
|
CDK9-IN-1 is a highly potent, selective CDK9 inhibitor with IC50 of 12 nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition. |
| PC-62821 |
CGP-74514A hydrochloride
|
CGP-74514A hydrochloride is a potent CDK1 inhibitor with IC50 of 25 nM. |
| PC-62680 |
NSC 625987
|
NSC 625987 is a potent, selective CDK4 inhibitor with IC50 of 0.2 uM, displays >500-fold selectivity over CDK2 (IC50 >100 uM for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E). . |
| PC-62678 |
Ryuvidine
|
Ryuvidine is a potent, selective CDK4 inhibitor with IC50 of 6.0 uM, displays >30-fold selectivity over CDK2 (IC50>100 uM). |
| PC-62314 |
Indisulam
|
Indisulam (E7070) is potent, sulfonamide, cell-cycle inhibitor that possesses antiproliferative activities, causes decrease in the S phase fraction along with G1 and/or G2 accumulation in various cancer cell lines. |
| PC-61659 |
SEL120-34A hydrochloride
|
SEL120-34A is an ATP-competitive, selective, orally active CDK8 inhibitor that inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50 of 4.4 nM and 10.4 nM, respectively. |
| PC-61658 |
SEL120-34A
|
SEL120-34A is an ATP-competitive, selective, orally active CDK8 inhibitor that inhibits kinase activities of CDK8/CycC and CDK19/CycC complexes with IC50 of 4.4 nM and 10.4 nM, respectively. |
| PC-61143 |
AZD 5597
|
A highly potent cyclin-dependent kinase (CDK) inhibitor with IC50 of 2 nM for both CDK1 and CDK2. |
| PC-61136 |
CDK2 inhibitor 73
|
A potent, selective CDK2 inhibitor with IC50 of 44 nM for CDK2/cyclin A, displays 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM).. |
| PC-61020 |
Cdc7 inhibitor 7c
|
A highly potent, selective and time-dependent Cdc7 kinase inhibitor with IC50 of 0.7 nM with slow dissociation property, with 200-fold and >14,000-fold selectivity over CDK2 and ROCK1, respectively. |
| PC-60894 |
Cortistatin A
|
A potent and selective inhibitor of mediator-associated kinase CDK8 (IC50=12 nM) and its paralogue CDK19. |
