Cat. No. |
Product Name |
Information |
PC-63183 |
Robenacoxib
|
Robenacoxib is a nonsteroidal anti-inflammatory drug (NSAID) used in veterinary medicine for the relief of pain and inflammation in cats and dogs, a Cyclooxygenase(COX)-1 and COX-2 inhibitor.. |
PC-62501 |
PTUPB
AKR1C3 inhibitor
|
PTUPB is a novel dual acting COX-2/sEH inhibitor with IC50 of 1.26 uM/0.9 nM, also is a potent AKR1C3 inhibitor with IC50 of 65 nM. |
PC-60430 |
ASP-6537
COX-1 inhibitor
|
ASP-6537 (FK 881, FR 122047) is a novel potent, selective, reversible cyclooxygenase-1 (COX-1) inhibitor with IC50 of 4.9 nM. |
PC-45989 |
(S)-( )-Ibuprofen
|
An enantiomer of Ibuprofen that more potently inhibits COX activity, thromboxane formation, and platelet aggregation than the (R)-form. |
PC-45290 |
Parecoxib
COX-2 inhibitor
|
Parecoxib (SC-69124) is a potent and selective COX-2 inhibito, is a water-soluble prodrug of valdecoxib. |
PC-42668 |
Flurbiprofen
|
A non-steroidal anti-inflammatory drug (NSAID). |
PC-42511 |
(R)-Flurbiprofen
|
A non-steroidal anti-inflammatory drug (NSAID). |
PC-21896 |
Celecoxib
COX-2 inhibitor
|
Celecoxib (SC 58635) is a potent selective inhibitor of COX-2 with IC50 of 40 nM, non-steroidal anti-inflammatory drug (NSAID). |
PC-20874 |
Valdecoxib
COX-2 inhibitor
|
Valdecoxib (SC 65872) is a potent and selective inhibitor of COX-2 with IC50 of 5 nM, shows no activity against COX-1. |
PC-20873 |
Etoricoxib
COX-2 inhibitor
|
Etoricoxib (MK-0663) is a potent, selective and orally active inhibitor of COX-2 with IC50 of 1.1 uM for COX-2 (LPS-induced prostaglandin E2 synthesis), shows no activity against COX-1. |
PC-20235 |
SC-58125
COX-2 inhibitor
|
SC-58125 is a potent, selective inhibitor of COX-2 with IC50 of 0.05 uM, without inhibition on COX-1 (IC50>10 uM). |
PC-20195 |
Lumiracoxib
COX-2 inhibitor
|
Lumiracoxib (COX-189) is a highly selective COX-2 inhibitor with IC50 of 0.14 uM in COX-2-expressing dermal fibroblasts, inhibits purified COX-2 with Ki of 0.06 uM, 50-fold selectivity over COX-1 (Ki=3 uM). |