| Cat. No. |
Product Name |
Information |
| PC-20195 |
Lumiracoxib
COX-2 inhibitor
|
Lumiracoxib (COX-189) is a highly selective COX-2 inhibitor with IC50 of 0.14 uM in COX-2-expressing dermal fibroblasts, inhibits purified COX-2 with Ki of 0.06 uM, 50-fold selectivity over COX-1 (Ki=3 uM). |
| PC-63065 |
Polmacoxib
|
Polmacoxib (CG-100649) is a novel NSAID proposed to inhibit both COX-2 and carbonic anhydrase (CA)-I/-II. |
| PC-62881 |
Chemocoxib A
|
Chemocoxib A is a highly potent, selective, cytotoxic COX-2 inhibitor with IC50 of 290 nM and 90 nM for wt mCOX-2 and R120Q COX-2 mutant respectively. |
| PC-62672 |
Tilmacoxib
|
Tilmacoxib (JTE-522) is a potent, selective inhibitor of cyclooxygenase-2 (COX-2) that inhibits human recombinant COX-2 with IC50 of 85 nM, dispalys no activity against COX-1 (IC50>100 uM). |
| PC-61664 |
SC-236
|
SC-236 (SC58236) is a potent, selective, orally active inhibitor of COX-2 with IC50 of 10 nM. |
| PC-61415 |
Vitacoxib
|
A potent, selective COX-2 inhibitor with IC50 of 0.34 ug/mL, >50-fold selectivity over COX-1 (IC50=19.4 ug/mL). |
| PC-45292 |
Ampiroxicam
|
The prodrug of piroxicam that is a nonsteroidal anti-inflammatory drug (NSAID).. |
| PC-45921 |
Acetaminophen
|
A well-known analgesic and antipyretic agent that selectively inhibits COX activities in the brain. |
| PC-45313 |
Deracoxib
|
A selective COX-2 inhibitor that is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).. |
| PC-45194 |
Rofecoxib
|
A potent, selective and orally active COX-2 inhibitor with IC50 of 26 nM for inhibition of the COX-2-dependent production of PGE2 in human osteosarcoma cells. |
| PC-45291 |
Parecoxib sodium
|
A potent and selective COX-2 inhibitor. |
| PC-45966 |
Etodolac
|
A nonsteroidal anti-inflammatory drug that acts as a non-selective inhibitor of COX with IC50 of 53.5 nM. |
