| Cat. No. |
Product Name |
Information |
| PC-63327 |
AT-130
HBV capsid inhibitor
|
AT-130 is a potent inhibitor of HBV capsid assembly, inhibits wild-type HBV replication with IC50 of 2.4 uM. |
| PC-63326 |
GLS4
|
GLS4 (Morphothiadin) is a potent inhibitor of HBV capsid assembly, inhibits HBV replication (EC50=62.24 nM). |
| PC-63323 |
AB-423
|
AB-423 is a novel potent, class II HBV capsid inhibitor that shows potent inhibition of HBV replication with EC50 of 0.08-0.27 uM, with no significant cytotoxicity (CC50>10 uM). |
| PC-22187 |
GS-6671
HBsAg inhibitor
|
GS-6671 is a potent, orally bioavailable inhibitor of HBV surface antigen (HBsAg) with EC50 of 5.8 nM in HepG2-NTCP assays, via inhibition of the human poly(A) polymerases PAPD5/7, promoting destabilization and degradation of HBV mRNA. |
| PC-22186 |
GS-8873
HBsAg inhibitor
|
GS-8873 is a potent, orally bioavailable inhibitor of HBV surface antigen (HBsAg) with EC50 of 4 nM in HepG2-NTCP assays, via inhibition of the human poly(A) polymerases PAPD5/7, promoting destabilization and degradation of HBV mRNA. |
| PC-21756 |
SAG-524
HBV inhibitor
|
SAG-524 (SAG524) is a potent and orally bioavailable small molecule inhibitor of HBV replication, reduces HBsAg and HBV-DNA (IC50 = 0.92 nM and 1.4 nM) by destabilizing HBV-RNA. |
| PC-21261 |
Alisporivir
Cyclophilin inhibitor
|
Alisporivir (Debio 025, DEBIO-025) is a non-immunosuppressive cyclophilin inhibitor derived from cyclosporin A (CsA) with IC50 of 30 nM (CypD PPIase activity ), inhibits HCV replication in vitro more potently than CsA. |
| PC-20678 |
AB-836
HBV capsid inhibitor
|
AB-836 is a next generation oral hepatitis B virus (HBV) capsid inhibitor that interacts with HBV core protein and demonstrates robust antiviral activity. |
| PC-20253 |
Bersacapavir
HBV capsid inhibitor
|
Bersacapavir (JNJ 56136379, JNJ-6379) is a potent HBV capsid assembly modulator, JNJ-6379 specifically and potently inhibits HBV replication with EC50 of 54 nM (HepG2.117 cells). |
| PC-20059 |
Neracorvir
HBV inhibitor
|
Neracorvir is a potent anti-HBV agent, targets HBV surface antigen. |
| PC-49649 |
E-CFCP
HBV inhibitor
|
E-CFCP is a novel long-acting nucleotide reverse transcriptase inhibitor (NRTI) against HBV, shows potent activity against HBV WTD1 and HBV WTC2 with IC50 of 1.8 and 0.7 nM, respectively. |
| PC-49567 |
Vebicorvir
HBV core inhibitor
|
Vebicorvir (ABI-H0731) is a first-generation hepatitis B virus (HBV) core protein inhibitor, exhibits selective inhibition of HBV DNA replication with EC50 from 173 nM to 307 nM. |
