| Cat. No. |
Product Name |
Information |
| PC-20913 |
Givinostat hydrochloride monohydrate
pan HDAC inhibitor
|
Givinostat (ITF-2357) is a potent, orally active, pan-HDAC inhibitor with IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. |
| PC-20784 |
Romidepsin
HDAC inhibitor
|
Romidepsin (FK228, NSC 63017, R 901228, Depsipeptide) is a natrual produrct from Chromobacterium violaceum as class I HDACs inhibitor, inhibits HDAC1, HDAC2, HDAC4, and HDAC6 with IC50s of 36 nM, 47 nM, 510 nM and 1400 nM, respectively. |
| PC-20671 |
TNG260
CoreDAC inhibitor
|
TNG260 (TNG-260) is a potent, CoREST-selective deacetylase (CoreDAC) inhibitor, inhibits HDAC1 with 10-fold selectivity over HDAC3 in cells. |
| PC-20479 |
Purinostat
Class I /IIb HDAC inhibitor
|
Purinostat is a potent, highly selective class I and IIb HDAC inhibitor with IC50 of 0.81, 1.4, 1.7, and 3.8 nM for class I HDAC1, 2, 3, and 8, and 11.5, 1.1 nM for class IIb HDAC 6 and 10, respectively. |
| PC-20478 |
Purinostat mesylate
Class I /IIb HDAC inhibitor
|
Purinostat mesylate is a potent, highly selective class I and IIb HDAC inhibitor with IC50 of 0.81, 1.4, 1.7, and 3.8 nM for class I HDAC1, 2, 3, and 8, and 11.5, 1.1 nM for class IIb HDAC 6 and 10, respectively. |
| PC-20402 |
SBI-46
HDAC inhibitor
|
SBI-46 (SBI 46) is an antiandrogen-equipped histone deacetylase (HDAC) inhibitor, strongly binds to androgen receptor (AR, IC50=8.4 nM) and potently inhibited HDACs and the proliferation of AR+ CRPC. |
| PC-20239 |
HO53
HDAC3 inhibitor
|
HO53 is a small moecule inducer of cathelicidin antimicrobial peptide gene (CAMP) expression in bronchial epithelium cells, HO53 is a histone deacetylase (HDAC) inhibitor, interacts directly with HDAC3. |
| PC-20238 |
RGFP963
class I HDAC inhibitor
|
RGFP963 (RGFP 963) is a potent, selective class I HDAC inhibitor with IC50 of 1.51 uM, 0.75 and 0.096 uM for HDAC1, HDAC2, and HDAC3, respectively. |
| PC-20237 |
RGFP966
HDAC3 inhibitor
|
RGFP966 (RGFP 966) is a potent, specific HDAC3 inhibitor with IC50 of 0.08 uM, without effective inhibition of any other HDACs at 15 uM. |
| PC-20197 |
TTA03-107
HDAC1 inhibitor
|
TTA03-107 is a potent, selective HDAC1 inhibitor with Ki of 3.22 and 17.6 nM for HDAC1/2, respectively. |
| PC-20141 |
HDAC10 inhibitor 10c
|
HDAC10 inhibitor 10c is a potent, selective HDAC10 inhibitor with IC50 of 20 nM, shows high specificity over HDAC6 and with no significant impact on class I HDACs. |
| PC-49844 |
NBM-T-L-BMX-OS01
HDAC8 inhibitor
|
NBM-T-L-BMX-OS01 (BMX, HDAC8 inhibitor) is a potent, selective and BB penetrant HDAC8 inhibitor with IC50 of 831 nM. |
