Cat. No. |
Product Name |
Information |
PC-38203 |
SRI-37264
HIV-1 Nef inhibitor
|
SRI-37264 (SRI 37264) is a small molecule inhibitor of HIV-1 Nef-mediated activation of the myeloid Src-family kinase Hck, blocks HIV-1 replication in macrophages and disrupts MHC-I downregulation. |
PC-36055 |
ABX464
|
Obefazimod (ABX464) is a novel class of anti-HIV small molecule targeting Rev-mediated viral RNA biogenesis, shows dose dependent inhibition of HIV-1 replication in stimulated PBMCs with IC50 of 0.1-0.5 uM. |
PC-35935 |
BMS-818251
HIV-1 inhibitor
|
BMS-818251 (BMS818251) is a novel potent, small-molecule inhibitor of HIV-1 entry with EC50 of 0.019 nM against e laboratory-adapted HIV-1 strain NL4-3. |
PC-35869 |
GS-6207
|
GS-6207 (GS6207, GS-CA1, Lenacapavir) is a potent, selective inhibitor of HIV-1 capsid function with potency and potential to be clinically effective against a broad range of HIV-1 strains. |
PC-35751 |
NSC260594
|
NSC260594 (NSC 260594) is a specific inhibitor of HIV-1 RNA packaging, which involves preventing the interaction of Gag with SL3 by stabilizing this small RNA stem-loop which then leads to stabilization of the global packaging signal region (psi or ψ). |
PC-35225 |
NBD-14189
|
NBD-14189 (NBD14189) is a novel potent HIV-1 entry antagonist with potency as low as 63 nM against some clinical isolates, target HIV-1 gp120.. |
PC-35156 |
KNI-1657
HIV-1 protease inhibitor
|
KNI-1657 (KNI1657) is a highly potent HIV-1 protease inhibitor (97% inhibition at 1 nM) with high sensitivity against lopinavir/ritonavir- or darunavir-resistant strains. |
PC-43512 |
TAK-779
CCR5 antagonist
|
TAK-779 is a potent, specific, nonpeptide CCR5 antagonist with Kd of 0.45 nM, antagonizes CCR2b to a lesser extent (27 nM) but does not affect CCR1, CCR3, or CCR4. |
PC-63542 |
PF-3450074
HIV capsid inhibitor
|
PF-3450074 (PF74) is a small molecule HIV capsid protein, destabilized the viral capsid in vitro. |
PC-63540 |
GS-9695
HIV integrase inhibitor
|
GS-9695 is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 1.2 nM. |
PC-43448 |
BMS-707035
|
BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity with IC50 of 15 nM.. |
PC-43417 |
Dolutegravir
|
Dolutegravir (GSK1349572) is a potent, next-generation HIV integrase (IN) inhibitor, inhibits HIV-1 integrase-catalyzed strand transfer with IC50 of 2.7 nM. |