| Cat. No. |
Product Name |
Information |
| PC-21658 |
AM-9022
Kif18A inhibitor
|
AM-9022 (AM9022) is a potent, selective and orally active mitotic kinesin KIF18A inhibitor with IC50 of 47 nM in kinesin-8 microtubule (MT)-ATPase motor assays. |
| PC-73188 |
Filanesib
KSP inhibitor
|
Filanesib (ARRY-520) is a potent, selective and noncompetitive kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM. |
| PC-72268 |
KIF18A inhibitor 24
KIF18A inhibitor
|
KIF18A inhibitor 24 is a highly potent, in vivo active inhibitor of mitotic kinesin KIF18A with IC50 of 61 nM. |
| PC-35945 |
GW406108X
|
GW406108X (GW-406108X, GW108X) is specific inhibitor of Kif15 (Kinesin-12) with IC50 of 0.82 uM in ATPase assays. |
| PC-63479 |
SR31527
|
SR31527 is a novel allosteric Kinesin-like protein KIFC1 inhibitor that inhibits microtubule-stimulated KIFC1 ATPase activity with IC50 of 6.6 uM, binds directly to KIFC1 with Kd of 25.4 nM. |
| PC-42882 |
SB-743921
|
SB-743921 is a potent, selective kinesin spindle protein (KSP) inhibitor with Ki of 0.1 nM, shows no activity against MKLP1, Kin2, Kif1A, Kif15, KHC, Kif4 and CENP-E. |
| PC-62648 |
Kinesore
|
Kinesore is a small molecule activator of kinesin-1 that inhibits KLC2-SKIP interaction with IC50 of 101 uM, Ki of 49 uM. |
| PC-62374 |
AZ82
|
AZ82 (KIFC1 inhibitor AZ82) is the first reported small molecule inhibitor of motor protein KIFC1 that inhibits the MT-stimulated KIFC1 enzymatic activity in an ATP-competitive and MT-noncompetitive manner with Ki of 43 nM. |
| PC-62340 |
S-Trityl-L-cysteine
|
S-Trityl-L-cysteine (NSC 83265) is a potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, inhibits basal ATPase activity (IC50=1 mM) and microtubule-activated ATPase activity of Eg5 (IC50=140 nM). |
| PC-62339 |
PVZB-1194
|
PVZB-1194 is a bis(hetero)aryl derivative that inhibits kinesin spindle protein (KSP) ATPase witn IC50 of 0.12 uM. |
| PC-62338 |
MK-0731
|
MK-0731 is a potent, selective kinesin spindle protein (KSP) inhibitor with IC50 of 2.2 nM, cell EC50 of 5.3 nM. |
| PC-62337 |
MK-8267
|
MK-8267 (SCH 2047069) is a potent, orally bioavailable, brain penetrant kinesin spindle protein (KSP) inhibitor with EC50 of 3 nM. |
