| Cat. No. |
Product Name |
Information |
| PC-35237 |
MELK inhibitor 17
MELK inhibitor
|
MELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM, >100-fold selectivity over CHK1, CAMKK2, NUAK1 and ERK2. |
| PC-61764 |
JW-7-25-1
MELK inhibitor
|
JW-7-25-1 is a potent MELK inhibitor with biochemical IC50 of 5.0 nM, also inhibits PIK3CA, mTOR, GSK3A and CDK7 with CI50 of 5-60 nM. |
| PC-61763 |
HTH-01-091
|
HTH-01-091 is a potent and selective, cell-permeable, ATP-competitive MELK inhibitor with biochemical IC50 of 10.5 nM. |
| PC-61630 |
KIN-281
MELK inhibitor
|
KIN-281 is a small molecule that inhibits multiple kinases including MELK and the non-receptor tyrosine kinase BMX with IC50 of 1.4 and 1.9 uM, respectively. |
| PC-42114 |
NVS-MELK8a hydrochloride
|
NVS-MELK8a hydrochloride (MELK8a hydrochloride) is a novel potent, and selective MELK inhibitor with IC50 of 2 nM. |
| PC-44481 |
OTS-167 hydrochloride
MELK inhibitor
|
OTSSP167 hydrochloride (OTS-167) is a highly potent, selective and orally active MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM. |
| PC-44480 |
OTS-167
MELK inhibitor
|
OTSSP167 (OTS167) is a highly potent, selective and orally active MELK (maternal embryonic leucine zipper kinase) inhibitor with IC50 of 0.41 nM. |
| PC-20606 |
NVS-MELK8a
MELK inhibitor
|
NVS-MELK8a (MELK8a) is a novel potent, and selective MELK inhibitor with IC50 of 2 nM. |
| PC-70141 |
Kinase inhibitor C1
|
A potent small molecule inhibitor of MELK kinase activity with IC50 of 42 nM. |
| PC-70140 |
MELK-T1
|
A novel, cell-permeable, potent and selective inhibitor of MELK kinase domain with IC50 of 37 nM. |
| PC-70139 |
MELK-T1 hydrochloride
|
A novel, cell-permeable, potent and selective inhibitor of MELK kinase domain with IC50 of 37 nM. |
