| Cat. No. |
Product Name |
Information |
| PC-21389 |
BNC105
Tubulin inhibitor
|
BNC105 is a small molecule tubulin polymerization inhibitor (IC50=3.0 uM) with potent antiproliferative and tumor vascular disrupting properties. |
| PC-21388 |
KGP618
Tubulin inhibitor
|
KGP618 is the phosphate prodrug salt of KGP591, which is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM. |
| PC-21387 |
KGP591
Tubulin inhibitor
|
KGP591 is a small molecule inhibitor of tubulin polymerization with IC50 of 0.57 uM, exhibits cytotoxicity against the MCF-7 and MDA-MB-231 human breast cancer cell lines with GI50 of 320 and 102 nM, respectively. |
| PC-20928 |
Epothilone A
Tubulin inhibitor
|
Epothilone A (Epo A) is a competitive inhibitor of the binding of [3H] paclitaxel to tubulin polymers with Ki of 0.6-1.4 uM. |
| PC-20673 |
EAPB02303
Microtubule inhibitor
|
EAPB02303 (EAPB 02303) is a novel microtubule-disrupting agent with in-vivo activity in PDAC and in-vitro synergy with Paclitaxel, inhibits A375 melanoma cell line with IC50 of 3 nM. |
| PC-49251 |
ELR510444
Microtubule disruptor
|
ELR510444 (ELR-510444) is a small molecule microtubule disruptor that directly interacts with tubulin at the colchicine-binding site, shows potent microtubule-disrupting activity. |
| PC-38804 |
CH-2-77 analogue 60c
Tubulin inhibitor
|
CH-2-77 analogue 60c is a potent colchicine-binding site tubulin inhibitor, inhibits tubulin polymerization and is effective against P-glycoprotein-mediated multiple drug resistance and taxol resistance. |
| PC-38803 |
CH-2-77
Tubulin inhibitor
|
CH-2-77 is a potent colchicine-binding site inhibitor (CBSI) targeting tubulin, shows potent anti-proliferative activity against a panel of cancer cells in vitro and efficacious anti-tumor effects in vivo. |
| PC-38550 |
Todalam
Tubulin inhibitor
|
Todalam is a novel small molecule tubulin inhibitor with IC50 of 8.8 uM against HeLa cells, fully inhibits microtubule formation with IC50 of 48 uM, acting as a reversible microtubule-destabilizing agent in vitro and in cells. |
| PC-72562 |
Microtubule inhibitor PP-13
Microtubule inhibitor
|
Microtubule inhibitor PP-13 is a novel microtubule-destabilizing agent, directly inhibits microtubule assembly by targeting the colchicine-binding site in β-tubulin. |
| PC-72275 |
IMB5476
Microtubule inhibitor
|
IMB5476 (IMB 5476) is a nitrobenzoate microtubule inhibitor, exerts broad-spectrum cytotoxicity against various human tumor cell lines (NCI-H460, IC50=144 nM). |
| PC-72173 |
PST-3
Microtubule inhibitor
|
PST-3 (Microtubule inhibitor PST-3) is a novel microtubule inhibitor exhibited broad-spectrum cellular cytotoxicity and in vivo potency with high safety. |
