| Cat. No. |
Product Name |
Information |
| PC-35822 |
6-MOMIPP
|
6-MOMIPP is a novel microtubule disruptor that targets the colchicine binding site on β-tubulin, induces mitotic arrest, caspase activation and loss of cell viability of U251 glioblastoma in vitro. |
| PC-35617 |
MP-HJ-1b
|
MP-HJ-1b is a novel potent inhibitor of microtubule and tumor cell growth, binds the colchicine pocket at the intra-dimer interface, depolymerizes microtubules and affects spindle formation. |
| PC-35599 |
VERU-111 analogue 13f
|
VERU-111 analogue 13f is a novel potent colchicine binding site inhibitor (CBSI) in tubulin with potential anticancer activities. |
| PC-35472 |
CKD-516
|
CKD-516 (Valecobulin, CKD516) is a potent beta-tubulin polymerization inhibitor with marked antitumor activity both in vitro and in vivo. |
| PC-35334 |
Plocabulin
|
Plocabulin (PM060184) is a novel tubulin-binding agent binding to αβ-tubulin dimer with nanomolar affinity, inhibits a panel of 23 tumor cell lines with GI50 of 20 pM-5 nM. |
| PC-35304 |
DZ-2384
|
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types. |
| PC-43449 |
ABT-751
|
ABT-751 (E-7010) is an orally active antimitotic agent that inhibits tubulin polymerization, exhibits consistent growth-inhibitory activities against a panel of human tumor cell lines (IC50=0.06-0.8 ug/mL). |
| PC-63320 |
FiVe1
|
FiVe1 is a vimentin binding small molecule that promotes vimentin disorganization and phosphorylation during metaphase, causes mitotic catastrophe, multinucleation, and the loss of stemness in cancer cells. |
| PC-42867 |
Vinorelbine ditartrate
|
Vinorelbine (KW-2307) is a vinca alkaloid chemotherapy agent that inhibits cancer cell mitosis through interaction with tubulin, inhibits HeLa cell proliferation with IC50 of 1.25 nM. |
| PC-42866 |
Vinorelbine
|
Vinorelbine (KW-2307) is a vinca alkaloid chemotherapy agent that inhibits cancer cell mitosis through interaction with tubulin, inhibits HeLa cell proliferation with IC50 of 1.25 nM. |
| PC-62674 |
PST-1
|
PST-1 is a photoswitchable inhibitor of microtubule with EC50 of 0.5 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines. |
| PC-62673 |
PST-1P
|
PST-1P is a photoswitchable inhibitor of microtubule with EC50 of 0.7 uM under 390 nm irradiation in the MDA-MB-231 human breast cancer cell lines. |
