| Cat. No. |
Product Name |
Information |
| PC-49781 |
MC0704
STAT3 inhibitor
|
MC0704 (MC-0704) is a novel synthetic STAT3 pathway inhibitor, exhibits potential antitumor activity in vitro and in vivo models in docetaxel-resistant TNBC cells. |
| PC-49596 |
SOST inhibitor S6
Sclerostin inhibitor
|
SOST inhibitor S6 is a small-molecule targeting Sclerostin (SOST), blocks STAT3 binding to SOST, inhibits breast cancer bone metastasis. |
| PC-47050 |
LLL12B
STAT3 inhibitor
|
LLL12B is a selective STAT3 inhibitor that suppresses Th17 development, specifically inhibits STAT3 and suppresses Th17 differentiation and expansion. |
| PC-38756 |
pan-IFN inhibitor 5k
Interferon inhibitor
|
pan-IFN inhibitor 5k is a potent and selective inhibitor of interferon-induced JAK-STAT signalling, blocks IFNγ activation of JAK-STAT signalling, also inhibits type I and III IFN-induced STAT phosphorylation in vitro. |
| PC-38627 |
STAT3 inhibitor N4
STAT3 inhibitor
|
STAT3 inhibitor N4 is a small molecule capable of inhibiting the STAT3 SH2 domain with IC50 of 0.57 uM, SPR KD of 1.04 uM, inhibits STAT3 dimerization and transcription in vitro and suppresses pancreatic cancer in vivo. |
| PC-70276 |
OPB-51602
|
A novel small molecule SH2 domain-targeting STAT3 inhibitor with IC50/Kd of 7.3/5 nM. |
