| Cat. No. |
Product Name |
Information |
| PC-61358 |
IRES-J007
IRES inhibitor
|
IRES-J007 is an improved IRES inhibitor that blocks IRES-hnRNP A1 binding, binds to a small pocket structure within the RRM-containing fragment of hnRNP A1 (UP1 fragment), inhibits cyclin D1 and c-MYC IRES activity to a greater extent compared with C11 (IRES-C11). |
| PC-60543 |
CBL0137
NF-κB inhibitor
|
CBL0137 (Curaxin CBL0137) is a histone chaperone FACT (facilitates chromatin transcription) and MYC signal inhibitor that markedly reduced tumor initiation and progression in vivo. |
| PC-60241 |
sAJM-589
c-Myc inhibitor
|
sAJM-589 (sAJM589) is a novel, potent small molecule Myc inhibitor that disrupts the Myc-Max leucine-zipper heterodimer with IC50 of 1.8 uM. |
| PC-42299 |
10074-G5
c-Myc inhibitor
|
10074-G5 is a small molecules that disrupts c-Myc-Max heterodimerization, binds to and distorts the bHLH-ZIP domain of c-Myc. |
| PC-21524 |
Isopomiferin
MYCN inhibitor
|
Isopomiferin is a prenylated isoflavonoid, collapses the tumor checkpoint module (TCM) and suppresses both MYCN and TEAD4 in MYCN-amplified NBL cells. |
| PC-21473 |
10074-A4
c-Myc inhibitor
|
10074-A4 is a specific small molecule inhibitor of c-Myc370-409 with binding Kd of 36.3 uM. |
| PC-20800 |
KI-MS2-008
Max homodimer stablizer
|
KI-MS2-008 is a small molecule Max binder that modulate Myc-driven transcription in cells (IC50=1.28 uM) and inhibit viable cell levels in a Myc-dependent manner. |
| PC-20799 |
NSC13728 hydrochloride
Max homodimer stablizer
|
NSC13728 hydrochloride is a specific small molecule stabilizer of the Max homodimer inhibiting Myc function, also inhibits Myc-Max heterodimerization. |
| PC-20798 |
NSC13728
Max homodimer stablizer
|
NSC13728 is a specific small molecule stabilizer of the Max homodimer inhibiting Myc function, also inhibits Myc-Max heterodimerization. |
| PC-38695 |
MYRA-B
c-MYC inhibitor
|
MYRA-B (NSC45641) is a small molecule that induces Myc-dependent apoptosis without affecting Myc transactivation or Myc/Max DNA binding. |
| PC-38694 |
MYRA-A
c-MYC inhibitor
|
MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF. |
| PC-38693 |
KSI-3716
c-MYC inhibitor
|
KSI-3716 is a small molecule c-MYC inhibitor that blocks c-MYC/MAX binding to target gene promoters, inhibits c-MYC mediated transcriptional activity at concentrations as low as 1 uM. |
