| Cat. No. |
Product Name |
Information |
| PC-25269 |
QH-ii-66
α5-GABAA receptor agonist
|
QH-ii-66 is a potent, selective agonist of α5-GABAA receptor (GABRA5). |
| PC-25268 |
SR-419
α5-GABAA receptor inhibitor
|
SR-419 is a BBB-impermeable, selective α5-GABAA receptor (GABRA5) inhibitor, shows specific binding to the benzodiazepine site of the GABRA5 receptor, exhibits potent peripheral analgesic effects. |
| PC-25067 |
EL-0052
GABAAR modulator
|
EL-0052 (Lorotomidate, 4-Fluoroetomidate) is a small molecule γ-aminobutyric acid A receptor (GABAAR) modulator, enhances GABAA receptors currents with EC50 of 0.98 uM. |
| PC-24988 |
GABAA receptor agonist CTMB
GABAA receptor agonist
|
CTMB is an allosteric agonist of GABAA receptors, positively modulates GABAA receptors and inhibits voltage-regulated sodium channels (NaVs) to suppress neuronal membrane depolarization. |
| PC-24815 |
Droperidol
CAS 548-73-2
|
Droperidol (Dehydrobenzperidol) is a butyrophenone pamine-2 receptor antagonist, inhibits the activation of GABA(A) and neuronal nicotinic receptors (nAChR) with IC50 of 12.6 nM and 5.8 μM, also specifically inhibits YTHDF2 and prevents associations of YTHDF2 with DDX1 and eIF3F. |
| PC-24505 |
Flumazenil
GABAA antagonist
|
Flumazenil is a central benzodiazepine receptor (IC50=9.91 nM) and competitive GABAA receptor antagonist, reverses the sedative effects of benzodiazepines on the central nervous system. |
| PC-24258 |
ENX-101
⍺2,3,5 GABAA receptor PAM
|
ENX-101 is a α2,α3,α5-selective γ-aminobutyric acid type A (GABAA) receptor partial positive allosteric modulator (PAM), deuterated analog of L-838,417. |
| PC-24174 |
Refisolone
GABAA antagonist
|
Refisolone is a potent GABAA receptor antagonist with potential for treatment of migraine. |
| PC-24158 |
Moxetomidate hydrochloride
GABAA agonist
|
Moxetomidate hydrochloride (ET-26 HCl, Methoxyethyl etomidate hydrochloride) is a novel etomidate analogue and short-acting anesthetic drug, a GABAA receptor agonist. |
| PC-24157 |
Moxetomidate
GABAA agonist
|
Moxetomidate (ET-26) is a novel etomidate analogue and short-acting anesthetic drug, a GABAA receptor agonist. |
| PC-24010 |
CGP55845 hydrochloride
GABAB antagonist
|
CGP55845 hydrochloride is a potent and selective GABAB receptor antagonist with IC50 of 6 nM, high selective over GABAA receptors. |
| PC-23662 |
Picrotoxin
GABAA receptor antagonist
|
Picrotoxin (Cocculin) is a natural noncompetitive antagonist of GABAA receptor (GABA AR), binds to the interface pocket on the GABAR, causes overstimulation and induces convulsions. |
