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Cat. No. Product Name Information
PC-49482

MLT-985

MALT1 inhibitor

MLT-985 (MLT985) is a potent, highly selective allosteric MALT1 inhibitor with biochemical IC50 of 3 nM, and 20 nM in IL-2 reporter gene assay (Jurkat T cells).
PC-36042

MLT-748

MALT1 inhibitor

MLT-748 (MLT748) is a potent, selective, allosteric inhibitor of MALT1 paracaspase with IC50 of 5 nM, does not show inhibitory activity against 22 other tested human proteases (IC50>100 uM).
PC-42938

MALT1 inhibitor MI-2

MALT1 inhibitor

MALT1 inhibitor MI-2 is a selective, irreversible MALT1 paracaspase inhibitor with IC50 of 5.84 uM, displays little activity against the related caspase family members caspase-3, -8, and -9.
PC-22030

ABBV-MALT1

MALT1 inhibitor

ABBV-MALT1 is a potent, selective, allosteric inhibitor of the MALT1 paracaspase with binding KD of 37 nM, exhibits potent biochemical inhibition of MALT1 protease activity with IC50 of 349 nM.
PC-20142

MALT1 inhibitor 37

MALT1 inhibitor

MALT1 inhibitor 37 is a potent, selective and oral bioavailable MALT1 inhibitor with IC50 of 93 nM, shows high potency for inhibiting IL-2 production with IC50 of 1.4 uM.
PC-49483

MLT-943

MALT1 inhibitor

MLT-943 is a potent and selective MALT1 protease inhibitor with IC50 of 40 nM in IL-2 reporter gene assay (Jurkat T cells), inhibits human PBMC IL-2 release with IC50 of 74 nM.
PC-49481

MLT-827

MALT1 inhibitor

MLT-827 is a potent and selective inhibitor of MALT1 paracaspase activity with IC50 of 5 nM.
PC-49480

MLT-231

MALT1 inhibitor

MLT-231 (MLT231) is a highly potent, selective, allosteric MALT1 inhibitor with biochemical IC50 of 9 nM, inhibits MALT1 cleavage of the BCL10 substrate with IC50 of 0.16 uM.
PC-49479

MALT1 inhibitor 8

MALT1 inhibitor

MALT1 inhibitor 8 is a potent, selective and orally bioavailable MALT1 inhibitor with cellular IC50 of 3.2 uM, binds to an induced allosteric site in MALT1.
PC-49478

Mepazine

MALT1 inhibitor

Mepazine is a potent, selective MALT1 paracaspase inhibitor with IC50 of 0.83 uM.
PC-49475

z-VRPR-fmk

MALT1 inhibitor

z-VRPR-fmk is a tetrapeptide inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) with Ki of 0.14 uM, shows complete inhibition at 1.25 uM.
PC-49440

RGT-068A

MALT1 inhibitor

RGT-068A is a potent selective MALT1 inhibitor.

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