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Chemical Structure : (Z)-4-Hydroxytamoxifen
CAS No.: 68047-06-3
Catalog No.: PC-45096Not For Human Use, Lab Use Only.
A major metabolite of tamoxifen, a well-known Estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $80 | In stock | |
| 10 mg | $112 | In stock | |
| 25 mg | $240 | In stock | |
| 50 mg | $440 | In stock |
Bulk size, bulk discount!
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A major metabolite of tamoxifen, a well-known Estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium; shows a 100-fold increased affinity for ER and approximately 100-times more potent than trans-tamoxifen in suppressing cell growth and plasminogen activator activity.
| M.Wt | 387.5139 | |
| Formula | C26H29NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 28 mg/mL |
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| Chemical Name/SMILES |
Phenol, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]- |
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1. Katzenellenbogen BS, et al. Cancer Res. 1984 Jan;44(1):112-9.
2. Desta Z, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75.
3. Crewe HK, et al. Drug Metab Dispos. 2002 Aug;30(8):869-74.
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