You are here:Home-Chemical Inhibitors & Agonists-PI3K/Akt/mTOR Pathway-PI3K

Request The Product List ofPI3K PI3K

Cat. No. Product Name CAS No. Information
PC-35552

PQR-530

1927857-61-1 PQR-530 (PQR530) is a potent, BBB penetrant, dual pan-PI3K/mTOR inhibitor with Kd of 0.3/1/6/11/10 nM for mTOR/PIK3CA/PIK3CB/PIK3CD/PIK3CG, respectively.
PC-63379

Inavolisib

2060571-02-8 GDC-0077 (Inavolisib, RG-6114) is a potent, highly isoform selective inhibitor of PI3Kα, with IC50 of 0.038 nM.
PC-43055

SAR405

1523406-39-4 SAR405 is a highly potent and selective PI3K class III isoform Vps34 inhibitor with IC50 of 1.2 nM, inhibits the formation of autophagosomes in GFP-LC3 cells with IC50 of 4 nM.
PC-42941

Umbralisib

1532533-67-7 Umbralisib (RP5264,TGR1202, TGR-1202) is a potent, selective, orally available PI3Kδ inhibitor with IC50 of 22 nM, 50-fold selectivity over PI3Kα/β and >10,000 fold over PI3Kγ.
PC-61959

DS-7423

1222104-37-1 DS-7423 is a novel potent, small-molecule dual inhibitor of PI3K/mTOR with IC50 of 15.6, 1143, 249, 262 and 34.9 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ, and mTOR  respectively.
PC-61127

PI3Kδ inhibitor 52

1911564-39-0 ZUN64390 is a potent, selective, and efficacious PI3Kδ inhibitor with IC50 of 1.7 nM, >100-fold selectivitity over PI3Kγ/α/β.
PC-60527

Parsaclisib

1426698-88-5 Parsaclisib (INCB050465) is a potent and highly selective PI3Kδ inhibitor with IC50 of < 1 nM (SPA).

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com