| Cat. No. |
Product Name |
Information |
| PC-63228 |
ML316
|
ML316 is a specific antifungal agent that fungal-selectively inhibits the mitochondrial phosphate carrier Mir1, exhibits potent antifungal activity against the moderatelyazole-resistant C. albicans strain CaCi-2 with MIC of 0.05 ug/ml. |
| PC-63050 |
Butenafine hydrochloride
|
Butenafine is a synthetic benzylamine antifungal that inhibits the synthesis of ergosterol by inhibiting squalene epoxidase. |
| PC-62617 |
APX001
|
APX001 (Fosmanogepix, E1210) is a novel broad-spectrum antifungal agent that inhibits the fungal protein Gwt1, demonstrates significantly acitive MIC50 and MIC90 values of 0.004 and 0.031 ug/ml (16 strains of C. auris). |
| PC-62615 |
PC945
|
Opelconazole (PC945) is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively. |
| PC-61753 |
VT-1161
|
VT-1161 (Oteseconazole) is a potent, highly-selective, and oral fungal CYP51 inhibitor with Kd of ≤ 39 nM. |
| PC-61752 |
VT-1598
|
VT-1598 is a potent, high-affinity, oral inhibitor of fungal sterol 14α-demethylase (CYP51B) with Kd of 13 nM. |
| PC-70224 |
F-901318
|
F-901318 (Olorofim) is a novel antifungal agent that inhibits A. fumigatus DHODH with IC50 of 44 nM. |
