Cat. No. |
Product Name |
CAS No. |
Information |
PC-35126 |
NCT-505
|
2231079-75-5 |
NCT-505 (NCT505) is a potent, selective, orally available ALDH1A1 inhibitor with IC50 of 7 nM (hALDH1A1), exhibits high specificity over other ALDH isozymes and unrelated dehydrogenases. |
PC-61351 |
DIMATE
|
350229-29-7 |
DIMATE is a novel irreversible, competitive, isoform-specific ALDH1 inhibitor, displays cytotoxic activity on human AML cell lines with IC50 of 1-15 uM. |
PC-45551 |
NCT-501
|
1802088-50-1 |
NCT-501 (NCT501) is a potent and highly selective inhibitor of ALDH1A1 with IC50 of 40 nM for hALDH1A1. |
PC-49053 |
IGUANA-1
|
2756014-24-9 |
IGUANA-1 is a potent, isoform-selective inhibitor of aldehyde dehydrogenase ALDH1B1, exhibits proteome-wide target specificity, and selectively blocks the growth of colon cancer spheroids and organoids. |
PC-72799 |
MCI-INI-3
|
1011366-31-6 |
MCI-INI-3 is a potent, selective, competitive inhibitor of ALDH1A3 (Ki=0.55 uM, shows poor inhibitory effect on the structurally related isoform ALDH1A1 (>140-fold selectivity). |
PC-72688 |
Dichloro-all-trans-retinone
|
2089135-65-7 |
Dichloro-all-trans-retinone (DAR) is an irreversible inhibitor of retinaldehyde dehydrogenase (RALDH/ALDH1A) with IC50 of 434/55/161 nM for RALDH1/RALDH2/RALDH3. |
PC-38166 |
KS100
|
2408477-53-0 |
ALDH inhibitor KS100 (KS100) is a novel, potent, multi-isoform ALDH inhibitor with IC50 of 207/1410/240 nM for ALDH1A1/ALDH2/ALDH3A1, respectively. |