You are here:Home-Chemical Inhibitors & Agonists-Epigenetics-Sirtuin

Request The Product List ofSirtuin Sirtuin

Cat. No. Product Name CAS No. Information
PC-35760

MDL-800

2275619-53-7 MDL-800 (MDL800) is a first-in-class, selective, cellular active SIRT6 allosteric activator, increases SIRT6 deacetylation activity with EC50 of 10.3 uM in RHKK-ac-AMC and FDL assays.
PC-60123

SirReal2

1848251-24-0 SirReal2 (MZ25) is a novel potent, selective Sirt2 inhibitor with IC50 of 0.435 uM.
PC-49081

MC3138

MC3138 is a potent and selective small-molecule SIRT5 activator, inhibits proliferation in SIRT5-low PDAC cell lines and organoids.
PC-47061

SRT2104

1093403-33-8 SRT2104 (GSK2245840) is a highly selective small molecule activator of the NAD+ dependent deacetylase SIRT1.
PC-38584

SIRT6 activator 12q

2601734-99-8 SIRT6 activator 12q (Compound 12q) is a potent, selective SIRT6 activator with EC1.5 value of 0.58 μM and EC50 value of 5.35 μM against SIRT6-dependent peptide deacetylation in FLUOR DE LYS assay.
PC-38580

SIRT6 activator CL5D

2488745-53-3 SIRT6 activator CL5D is a novel small-molecule activator of SIRT6 deacetylation, stimulates 4-fold activation of SIRT6 (1 uM) against H3K9ac (20 uM) at 3 uM.
PC-38543

AGK2

304896-28-4 AGK2 is a cell-permeable, selective inhibitor of SIRT2 with IC50 of 3.2 uM, shows minimally affects either SIRT1 or SIRT3 at 10-fold higher levels.

Request The Product List

* Indicates a Required FieldYour information is safe with us.

  • *Product List:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Country:
  • Additional Information:

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com