| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35856 |
UBCS039
|
358721-70-7 |
UBCS039 (UBCS-039) is the first synthetic activator of the NAD+-dependent protein lysine deacetylase SIRT6 with EC50 of 38 uM. |
| PC-35760 |
MDL-800
|
2275619-53-7 |
MDL-800 (MDL800) is a first-in-class, selective, cellular active SIRT6 allosteric activator, increases SIRT6 deacetylation activity with EC50 of 10.3 uM in RHKK-ac-AMC and FDL assays. |
| PC-63242 |
MC3482
|
|
MC3482 is a potent, specific SIRT5 inhibitor, increases the ammonia content in cells leading to autophagy and mitophagy, shows selective SIRT5 inhibition vs SIRT1-3.. |
| PC-60123 |
SirReal2
|
1848251-24-0 |
SirReal2 (MZ25) is a novel potent, selective Sirt2 inhibitor with IC50 of 0.435 uM. |
| PC-20271 |
40569Z
|
|
40569Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer. |
| PC-20270 |
2800Z
|
|
2800Z is a specific SIRT7 inhibitor, significantly inhibits SIRT7 deacetylation activity without effects on SIRT1 and SIRT6 activities, induces apoptosis and increases chemosensitivity to sorafenib in human liver cancer. |
| PC-20269 |
MDL-811
|
|
MDL-811 (MDL811) is a potent, selective and allosteric SIRT6 activator with EC50 of 5.7 uM (activated SIRT6 deacetylation), two-fold greater activity than MDL-800 (EC50=12.3 uM, Cat# 35760). |
