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Cat. No. Product Name Information
PC-21693

SBP7455

ULK1/2 inhibitor

SBP-7455 is a potent, selective and orally active ULK1/2 inhibitor with IC50 of 13 nM (ULK1) and 476 nM (ULK2) in ADP-Glo assays, selectively blocks autophagic flux in TNBC cell lines.
PC-21692

MR-2088

ULK1/2 inhibitor

MR-2088 is a potent and selective ULK1/2 inhibitor with IC50 of 2.0 nM and MST Kd value of 1.5-4.4 nM (ULK1), efficiently inhibits autophagy.
PC-72327

DCC-3116

ULK1/2 inhibitor

DCC-3116 (DCC3116) is a first-in-class, selective inhibitor of ULK1/2 kinases (IC50=4.7/35 nM) and autophagy.
PC-35708

ULK-100

ULK1 inhibitor

ULK-100 (ULK100) is a potent and selective ULK1 inhibitor with in vitro IC50 of 1.6 nM, inhibits ULK2 with IC50 of 2.6 nM.
PC-35707

ULK-101

ULK1/2 inhibitor

ULK-101 (ULK101) is a potent and selective ULK1 inhibitor with in vitro IC50 of 8.3 nM, inhibits ULK2 with IC50 of 30 nM.
PC-63368

BL-918

ULK1 inhibitor

BL-918 is a small molecule activator of ULK1 with EC50 of 24 nM (243% kinase activity at 100 nM), induces autophagy via the ULK complex in SH-SY5Y cells.
PC-43328

MRT67307

ULK inhibitor

MRT67307 is a potent, dual inhibitor of IKKε and TBK-1 with IC50 of 160 and 19 nM at 0.1 mM ATP in vitro, also potently inhibit ULK1 and ULK2 in vitro (IC50=45 and 38 nM) and block autophagy in cells.
PC-63085

LYN-1604

ULK1 activator

LYN-1604 is a potential ULK1 agonist (enzymatic activity=195.7% at 100 nM and IC50=1.66 uM against MDA-MB-231 cells), displays a good effect on ULK1 activation with an EC50 of 18.94 nM.
PC-62383

ULK1-IN-1

ULK1 inhibitor

ULK1-IN-1 highly potent ULK1 inhibitor with IC50 of 8 nM, with no enough selectivity but sufficient potency, a cellular probe of autophagy..
PC-60144

SR-20295

ULK1 inhibitor

SR-20295 (SR20295) is a novel potent ULK1 inhibitor with IC50 of 45 nM.
PC-60143

SR-19871

ULK1 inhibitor

SR-19871 is a novel potent ULK1 inhibitor with IC50 of 11 nM.
PC-42021

MRT68921 hydrochloride

ULK1/2 inhibitor

MRT-68921 hydrochloride (MRT68921) is a potent, relatively specific inhibitor of both ULK1 and ULK2 with IC50 of 2.9 and 1.1 nM, respectively.

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