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Cat. No. Product Name CAS No. Information
PC-35337

ζ-Stat

3316-02-7 ζ-Stat (1,3,6-Naphthalenetrisulfonic acid) is a novel PKC-zeta (PKC-ζ) specific inhibitor with IC50 of 5 uM, showed only 13% inhibition on PKC-I at 20 uM.
PC-63489

PKCiota-IN-49

2230055-52-2 PKCiota-IN-49 is a potent and selective inhibitor of Protein Kinase C iota (PKC-ι) with IC50 of 2.8 nM, >20-fold selectivity over PKC-α (IC50=71 nM) and PKC-β (IC50=350 nM).
PC-62375

BJE6-106

1564249-38-2 BJE6-106 (B106) is a potent, selective PKCδ inhibitor with IC50 of 50 nM, displays excellent selectivity over classical PKC isozymes (a 1,000-fold PKCδ selectivity over PKCα).
PC-60994

AS2521780

1214726-89-2 AS2521780 is a potent, selective, orally bioavailable PKCθ inhibitor that inhibits combinant human PKCθ enzyme with IC50 of 0.48 nM, >30-fold higher than other PKC isoforms.
PC-38836

Z640

353793-07-4 Z640 is a novel non-selective atypical PKC (aPKC) agonist, increases PKCζ and PKCι kinase activity with EC50 of 1.09 and 3.47 µM in vitro kinase activity assays, respectively.
PC-38356

Darovasertib

1874276-76-2 Darovasertib (LXS 196, IDE 196) is a selectve, oral small molecule protein kinase C (PKC) inhibitor, demonstrating promising efficacy in metastatic uveal melanoma (MUM) combined with Crizotinib.
PC-73059

NP627

412962-32-4 NP627 (NP-627) is a specific small-molecule inhibitor of protein kinase C deltaI (PKCδI) with Kd of 1 nM.

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