| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-35414 |
GSK621
|
1346607-05-3 |
GSK621 (GSK-621) is a potent, specific AMPK agonist (activator), induces cytotoxicity in AML (IC50=13-30 uM) but not in normal hematopoietic cells. |
| PC-35331 |
BAY-3827
|
2377576-35-5 |
BAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK as tool compound to evaluate the therapeutic potential of AMPK inhibition in MYC-dependent tumors. |
| PC-62774 |
PF-06685249
|
1467059-70-6 |
PF-06685249 (PF06685249, PF-249) is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 12 nM for α1β1γ1-AMPK. |
| PC-62013 |
MK-3903
|
1219737-12-8 |
MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM. |
| PC-60632 |
PF-06409577
|
1467057-23-3 |
PF-06409577(PF06409577, PF 6409577) is a potent, selective AMPK β1-containing isoforms activator with TR-FRET EC50 of 7.0 and 6.8 nM for α1β1γ1 and α2β1γ1, respectively. |
| PC-60179 |
EX-229
|
1219739-36-2 |
EX-229 is a small molecule AMPK activator that dose-dependently increases AMPK activity of α1-, α2-, β1- and β2-containing complexes at 50 uM. |
| PC-60137 |
MK-8722
|
1394371-71-1 |
MK-8722 is a potent, selective, allosteric pan-AMPK activator with EC50 of 1-60 nM for all 12 mammalian AMPK isoforms. |
