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Request The Product List ofAMPK AMPK

Cat. No. Product Name CAS No. Information
PC-47024

PXL770

1523493-53-9 PXL770 is a novel orally bioavailable, small-molecule direct AMPK activator with EC50 of 16.2, 42.1 and 64 nM for α1β1γ1, α1β1γ2 and α1β1γ3, directly increases AMPK activity by both allosteric activation and protection from dephosphorylation.
PC-35414

GSK621

1346607-05-3 GSK621 (GSK-621) is a potent, specific AMPK agonist (activator), induces cytotoxicity in AML (IC50=13-30 uM) but not in normal hematopoietic cells.
PC-35331

BAY-3827

2377576-35-5 BAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK as tool compound to evaluate the therapeutic potential of AMPK inhibition in MYC-dependent tumors.
PC-62774

PF-06685249

1467059-70-6 PF-06685249 (PF06685249, PF-249) is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 12 nM for α1β1γ1-AMPK.
PC-62013

MK-3903

1219737-12-8 MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM.
PC-61181

MT47-100

1179347-23-9 MT47-100 is a novel potent, allosteric, simultaneously direct activator and inhibitor of AMPK complexes containing the β1 or β2 isoform, respectively.
PC-60632

PF-06409577

1467057-23-3 PF-06409577(PF06409577, PF 6409577) is a potent, selective AMPK β1-containing isoforms activator with TR-FRET EC50 of 7.0 and 6.8 nM for α1β1γ1 and α2β1γ1, respectively.

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