| Cat. No. |
Product Name |
CAS No. |
Information |
| PC-47024 |
PXL770
|
1523493-53-9 |
PXL770 is a novel orally bioavailable, small-molecule direct AMPK activator with EC50 of 16.2, 42.1 and 64 nM for α1β1γ1, α1β1γ2 and α1β1γ3, directly increases AMPK activity by both allosteric activation and protection from dephosphorylation. |
| PC-35414 |
GSK621
|
1346607-05-3 |
GSK621 (GSK-621) is a potent, specific AMPK agonist (activator), induces cytotoxicity in AML (IC50=13-30 uM) but not in normal hematopoietic cells. |
| PC-35331 |
BAY-3827
|
2377576-35-5 |
BAY-3827 (BAY3827) is a potent, selective inhibitor of AMPK as tool compound to evaluate the therapeutic potential of AMPK inhibition in MYC-dependent tumors. |
| PC-62774 |
PF-06685249
|
1467059-70-6 |
PF-06685249 (PF06685249, PF-249) is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 12 nM for α1β1γ1-AMPK. |
| PC-62013 |
MK-3903
|
1219737-12-8 |
MK-3903 is a potent and selective, direct and oral AMPK activator with EC50 of 9 nM. |
| PC-61181 |
MT47-100
|
1179347-23-9 |
MT47-100 is a novel potent, allosteric, simultaneously direct activator and inhibitor of AMPK complexes containing the β1 or β2 isoform, respectively. |
| PC-60632 |
PF-06409577
|
1467057-23-3 |
PF-06409577(PF06409577, PF 6409577) is a potent, selective AMPK β1-containing isoforms activator with TR-FRET EC50 of 7.0 and 6.8 nM for α1β1γ1 and α2β1γ1, respectively. |
