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Request The Product List ofHedgehog (Hh) Hedgehog (Hh)

Cat. No. Product Name CAS No. Information
PC-60477

TAK-441

1186231-83-3 A highly potent, orally active hedgehog signaling (Hh) inhibitor with IC50 of 4.4 nM in Gli-luc reporter assays.
PC-70165

RUSKI-201

1458031-48-5 A potent, selective and cell active Hedgehog acyltransferase (Hhat) inhibitor with IC50 of 0.87 uM.
PC-45464

RU-SKI 43 hydrochloride

A small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM.
PC-45463

RU-SKI 43

1043797-53-0 A small molecule inhibitor of Hhat (Hedgehog acyltransferase) with IC50 of 0.85 uM.
PC-42258

Ciliobrevin A

302803-72-1 A small molecule Hedgehog pathway inhibitor (IC50=7 uM) that acts downstream of Su(fu) to modulate Gli processing, activation or trafficking.
PC-45147

Cyclopamine

4449-51-8 A natural steroidal alkaloid that inhibits hedgehog (Hh) signaling with IC50 of 46 nM.
PC-49040

HhAg1.5

612542-14-0 HhAg1.5 (SAg1.5) is a small molecule Hedgehog agonist with EC50 of 1 nM, induces cilia translocation of SMO and GLI transcription factor activation, efficiently generates expandable liver stem cells (LSCs) in vitro.

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