| Cat. No. |
Product Name |
Information |
| PC-22238 |
BMS-986189
PD-1/PD-L1 inhibitor
|
BMS-986189 is a macrocyclic thioether peptide antagonist of the PD-1/PD-L1 interaction with IC50 of 1.03 nM. |
| PC-20282 |
YPD-29B
PD-L1 inhibitor
|
YPD-29B is a potent, specific programmed cell death ligand 1 (PD-L1) inhibitor, effectively blocks the binding of PD-1 and PD-L1 with IC50 of 0.08 pM in HTRF protein-protein interaction assays. |
| PC-20281 |
IMMH-010
PD-L1 inhibitor
|
IMMH-010 (YPD-30) is an ester prodrug of YPD-29B, a high potent PD-L1 inhibitor (IC50=0.08 pM), YPD-30 is a potent PD-L1 inhibitor with IC50 of 45.2 nM in HTRF assays. |
| PC-20280 |
IMMH-010 maleate
PD-L1 inhibitor
|
IMMH-010 maleate (YPD-30) is an ester prodrug of YPD-29B, a high potent PD-L1 inhibitor (IC50=0.08 pM), YPD-30 is a potent PD-L1 inhibitor with IC50 of 45.2 nM in HTRF assays. |
| PC-20279 |
MAX10181
PD-L1 inhibitor
|
MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice. |
| PC-49504 |
PD-L1 inhibitor S4-1
PD-L1 inhibitor
|
PD-L1 inhibitor S4-1 is a novel small-molecule inhibitor of PD-L1, effectively alters the PD-L1/PD-1 interaction, induces PD-L1 dimerization and internalization. |
| PC-49402 |
PD-1 inhibitor SCL-1
PD-1 inhibitor
|
PD-1 inhibitor SCL-1 is a potent small molecule inhibitor of PD-1/PD-L1 binding and exerts potent antitumor effects. |
| PC-49098 |
BMS136
PD-L1 inhibitor
|
BMS136 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 96.7 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1. |
| PC-49097 |
BMS135
PD-1/PD-L1 inhibitor
|
BMS135 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 79.1 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1. |
| PC-38391 |
Evixapodlin
PD-1/PD-L1 inhibitor
|
Evixapodlin (GS-4224) is a highly potent, small molecule human PD-1/PD-L1 protein-protein interaction inhibitor with IC50 of 0.213 nM, exhibits potential anticancer and antiviral activities. |
| PC-73047 |
PD-L1 inhibitor 4
PD-L1 inhibitor
|
PD-L1 inhibitor 4 is a small molecule inhibitor of PD-1/PD-L1 with SPR KD of 0.079 nM. |
| PC-72848 |
INCB086550
PD-1/PD-L1 inhibitor
|
INCB086550 (INCB 086550) is a potent, selective small-molecule inhibitor of PD-L1, inhibits PD-L1/PD-1 interaction with IC50 of 3.1, 4.9 and 1.9 nM for human, cynomolgus and rat PD-L1 in HTRF-based assays. |
