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Request The Product List ofPD-1/PD-L1 PD-1/PD-L1

Cat. No. Product Name Information
PC-20282

YPD-29B

PD-L1 inhibitor

YPD-29B is a potent, specific programmed cell death ligand 1 (PD-L1) inhibitor, effectively blocks the binding of PD-1 and PD-L1 with IC50 of 0.08 pM in HTRF protein-protein interaction assays.
PC-20281

IMMH-010

PD-L1 inhibitor

IMMH-010 (YPD-30) is an ester prodrug of YPD-29B, a high potent PD-L1 inhibitor (IC50=0.08 pM), YPD-30 is a potent PD-L1 inhibitor with IC50 of 45.2 nM in HTRF assays.
PC-20280

IMMH-010 maleate

PD-L1 inhibitor

IMMH-010 maleate (YPD-30) is an ester prodrug of YPD-29B, a high potent PD-L1 inhibitor (IC50=0.08 pM), YPD-30 is a potent PD-L1 inhibitor with IC50 of 45.2 nM in HTRF assays.
PC-20279

MAX10181

PD-L1 inhibitor

MAX10181 (MAX-10181) is an orally active small molecule PD-L1 inhibitor, shows similar efficacy as Durvalumab in the head to head test of human PD-L1 knock-in MC38 cell line in human PD-1 knock-in mice.
PC-49504

PD-L1 inhibitor S4-1

PD-L1 inhibitor

PD-L1 inhibitor S4-1 is a novel small-molecule inhibitor of PD-L1, effectively alters the PD-L1/PD-1 interaction, induces PD-L1 dimerization and internalization.
PC-49402

PD-1 inhibitor SCL-1

PD-1 inhibitor

PD-1 inhibitor SCL-1 is a potent small molecule inhibitor of PD-1/PD-L1 binding and exerts potent antitumor effects.
PC-49099

5J89LIG

PD-1/PD-L1 inhibitor

5J89LIG is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 18.0 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.
PC-49097

BMS135

PD-1/PD-L1 inhibitor

BMS135 is a small molecule h-PD1/h-PD-L1 interaction inhibitor with IC50 of 79.1 nM, bind specifically to hPD-L1 through a unique mode of action, induces the dimerization of hPD-L1.
PC-38391

Evixapodlin

PD-1/PD-L1 inhibitor

Evixapodlin (GS-4224) is a highly potent, small molecule human PD-1/PD-L1 protein-protein interaction inhibitor with IC50 of 0.213 nM, exhibits potential anticancer and antiviral activities.
PC-73047

PD-L1 inhibitor 4

PD-L1 inhibitor

PD-L1 inhibitor 4 is a small molecule inhibitor of PD-1/PD-L1 with SPR KD of 0.079 nM.
PC-72848

INCB086550

PD-1/PD-L1 inhibitor

INCB086550 (INCB 086550) is a potent, selective small-molecule inhibitor of PD-L1, inhibits PD-L1/PD-1 interaction with IC50 of 3.1, 4.9 and 1.9 nM for human, cynomolgus and rat PD-L1 in HTRF-based assays.
PC-72764

ZE132

PD-1/PD-L1 inhibitor

ZE132 is a potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with IC50 of <0.1 nM.

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